BDBM377610 3-({[3-methoxy-4-(1H-1,2,3,4-::US10266495, Compound I-22
SMILES COc1cc(NCc2cc3ccc(C)cc3[nH]c2=O)ccc1-n1cnnn1
InChI Key InChIKey=BPKREDZWJFPBSA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 377610
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics
Curated by ChEMBL
Forma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 303nMAssay Description:Inhibition of human Myc-DDK-tagged IDH1 R132H mutant assessed as reduction in NADPH consumption pre-incubated for 15 mins followed by alpha-ketogluta...More data for this Ligand-Target Pair